first offinformal a) before doing anything else 先，首先 First off I’d like you all to fill in an evaluation sheet. 首先我想请各位填写一张评估表。
b) used before saying the first of several things you want to say, especially when you are annoyed 首先〔用于想说的几件事之前，尤用于生气时〕 First off I didn’t agree with the comments in your email. 首先，我不同意你电子邮件里的意见。
first off• Well, first off, I want to know what you've done with the money I gave you.
→ first off at first2(1)